Abstract Background Circular RNAs (circRNAs) have emerged as vital regulators of the initiation and progression of diverse kinds of human cancers.In this study, we explored the role of hsa_circ_0000231 and its downstream pathway in CRC.Methods The expression profile of circRNAs in 5 pairs of CRC tissues and adjacent normal tissues were analyzed by
Introduction: Compromised alveolar ridge in vertical and horizontal dimension is a common finding in Counter Base patients visiting practitioners for dental prosthesis.Various treatment modalities are available for correction of deficient ridges among which alveolar distraction osteogenesis is one.Aim: To study the efficacy of alveolar distraction
Abstract Background Neuroblastoma (NB) patients with MYCN amplification or overexpression respond poorly to current therapies and exhibit extremely poor clinical outcomes.PI3K-mTOR signaling-driven deregulation of protein synthesis is very common in NB and various other cancers that promote MYCN stabilization.In addition, both the MYCN and mTOR sig
Sickle cell disease (SCD) is an inherited disorder prevalent in many areas of the world including Africa, Middle East and parts of India.It is characterized by repetitive episodes of vaso- occlusive (VOC) process, leading to recurrent painful episodes, hemolytic anemia and predisposition to infection.Although VOC is a leading manifestation of SCD,